All Men's Blood Tests
Bowel Cancer Risk Test Clinic test
Genetic risk

Bowel Cancer Risk Test

Looks for inherited changes in 13 genes linked to bowel cancer and polyp syndromes — including the Lynch syndrome genes (MLH1, MSH2, MSH6, PMS2, EPCAM), APC and MUTYH.

Price £620 £588.99
Covers 13 genes
Type Clinic visit · ~15 min
Book just this test
Blood sample for DNA analysis — taken at 44 Crawford Street, Marylebone
No preparation needed. Bring details of any family history you know of.
Results explained by our clinical team
About this test

Everything you need to know about Bowel Cancer Risk Test

Around one in twenty bowel cancers is linked to a known inherited gene change, and in those families the cancer tends to arrive earlier than the NHS screening age. This test analyses 13 genes — APC, BMPR1A, EPCAM, MLH1, MSH2, MSH6, MUTYH, PMS2, PTEN, SMAD4, STK11, POLD1 and POLE — covering Lynch syndrome, familial adenomatous polyposis and the rarer polyposis syndromes.

A genetic test looks at the DNA you were born with. It tells you about inherited likelihood, not certainty: a variant can raise your risk without meaning you will develop the condition, and a clear result does not remove the everyday risk everyone carries. Results are explained to you by our clinical team, and we will say when a conversation with your GP or a genetics service is the right next step. A variant typically leads to a recommendation for earlier and more regular colonoscopy, which is one of the most effective preventive steps in medicine.

What's measured

What's included

13 genes in this test

APC BMPR1A EPCAM MLH1 MSH2 MSH6 MUTYH PMS2 PTEN SMAD4 STK11 POLD1 POLE
Who it's for

Worth considering if

  • A parent, sibling or child diagnosed with bowel cancer, especially under 50
  • Several relatives with bowel, womb, ovarian or stomach cancer (a Lynch pattern)
  • A family history of large numbers of bowel polyps
  • Deciding whether to start bowel screening earlier than the national programme
Important: A genetic test describes inherited likelihood, not certainty, and is not suitable for everyone. Our clinical team talks it through with you before the sample is taken and explains the result afterwards, including when a conversation with your GP or a genetics service is the right next step.
What to expect

Your visit

1

Book online

Add this test — and any others — to your booking, pick a time at the clinic and pay online. No preparation needed. Bring details of any family history you know of.

2

Your visit

About 15 minutes at 44 Crawford Street, Marylebone. Our clinical team takes your sample (blood sample for dna analysis) and answers any questions.

3

Results explained

The laboratory analyses your sample and your results are released to your secure account with a written explanation from our clinical team — and a call where something needs talking through.

Frequently Asked

Bowel Cancer Risk Test — FAQs

Does this test detect bowel cancer?
No. It looks at inherited risk, not at whether cancer or polyps are present now. Symptoms such as bleeding, a change in bowel habit or unexplained weight loss should be seen by your GP without waiting for a genetic result. The Bowel Blood & Inflammation home kit is a separate test for current signs.
What is Lynch syndrome?
An inherited condition caused by changes in MLH1, MSH2, MSH6, PMS2 or EPCAM that raises the risk of bowel cancer and some other cancers. People with Lynch syndrome are offered regular colonoscopy from a young age, which greatly reduces the risk.
What happens if a variant is found?
Our clinician explains what the specific change means for you and your relatives, and we recommend a conversation with your GP about referral to a genetics service and a surveillance plan.
How long do results take?
Genetic analysis takes longer than a routine blood test. We give you the expected turnaround at your appointment and arrange a results conversation once the report is back.
Where is the test done?
44 Crawford Street, London W1H 1JS — a short walk from Marylebone and Edgware Road stations. Your sample is taken at the clinic by our clinical team; you do not need to bring anything.
How long does the appointment take?
About 15 minutes. If you have booked several tests they are all done in the same visit.
Can I book several tests at once?
Yes. Use “Add to booking” on each test and then “Book” in the bar at the bottom — they go into one appointment and one payment. Home test kits are ordered separately, because they are posted to you.
How do I pay, and can I cancel?
Pay online when you book — by card or bank transfer — or at the clinic where that option is offered. You can cancel or reschedule up to 24 hours before your appointment for a full refund.
How do I get my results?
Results are released to your secure account and explained by our clinical team in a written summary, with a call where something needs talking through. Turnaround depends on the test: routine blood panels are quicker than genetic or DNA analysis, and we tell you what to expect at your appointment.
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