All Women's Blood Tests
Coeliac Disease Test Clinic test
Genetic risk · coeliac disease

Coeliac Disease Test

HLA-DQ genotyping — the test that can effectively rule coeliac disease out. Almost everyone with coeliac disease carries HLA-DQ2 or HLA-DQ8; if you carry neither, coeliac disease is very unlikely to be the cause of your symptoms.

Price £134 £106.99
Covers 1 gene
Type Clinic visit · ~15 min
Book just this test
Blood sample for DNA analysis — taken at 44 Crawford Street, Marylebone
No preparation needed — and no need to eat or avoid gluten beforehand.
Results explained by our clinical team
About this test

Everything you need to know about Coeliac Disease Test

Coeliac disease is an autoimmune reaction to gluten that damages the lining of the small intestine, causing anything from bloating, diarrhoea and tiredness to anaemia, weight loss and bone thinning. It is common — around one in 100 people — and most are undiagnosed.

This test reads your HLA-DQ genes. Carrying HLA-DQ2 or HLA-DQ8 is almost a prerequisite for coeliac disease, so a negative result makes the condition very unlikely and lets you and your GP look elsewhere for the cause of your symptoms. A positive result does not mean you have coeliac disease — around a third of people carry these genes — but it means it cannot be ruled out, and antibody testing (while still eating gluten) is the next step.

What's measured

What's included

1 gene in this test

HLA-DQ
Who it's for

Worth considering if

  • Digestive symptoms you suspect are gluten-related
  • Unexplained iron-deficiency anaemia, tiredness or early bone thinning
  • A parent, sibling or child with coeliac disease
  • Type 1 diabetes or autoimmune thyroid disease, which raise the chance of coeliac disease
Important: A genetic test describes inherited likelihood, not certainty, and is not suitable for everyone. Our clinical team talks it through with you before the sample is taken and explains the result afterwards, including when a conversation with your GP or a genetics service is the right next step.
What to expect

Your visit

1

Book online

Add this test — and any others — to your booking, pick a time at the clinic and pay online. No preparation needed — and no need to eat or avoid gluten beforehand.

2

Your visit

About 15 minutes at 44 Crawford Street, Marylebone. Our clinical team takes your sample (blood sample for dna analysis) and answers any questions.

3

Results explained

The laboratory analyses your sample and your results are released to your secure account with a written explanation from our clinical team — and a call where something needs talking through.

Frequently Asked

Coeliac Disease Test — FAQs

I already avoid gluten — does that affect this test?
No. The genetic result does not change with diet, which is exactly why this test is useful for people who went gluten-free before being tested. Antibody tests, by contrast, need you to be eating gluten.
What does a positive result mean?
That you carry HLA-DQ2 and/or HLA-DQ8 and coeliac disease is possible. About one in three people carry these genes and most never develop coeliac disease. The next step, if you have symptoms, is coeliac antibody testing while eating gluten — the Coeliac Antibody home kit, or via your GP.
Can this diagnose coeliac disease?
No. It can make it very unlikely (negative) or possible (positive). Diagnosis is confirmed with antibodies and, usually, a biopsy arranged by a gastroenterologist.
Should I stop eating gluten after a positive result?
Not before the diagnosis is confirmed. Going gluten-free first makes the confirmatory tests unreliable. Our clinician explains the right order of steps.
Where is the test done?
44 Crawford Street, London W1H 1JS — a short walk from Marylebone and Edgware Road stations. Your sample is taken at the clinic by our clinical team; you do not need to bring anything.
How long does the appointment take?
About 15 minutes. If you have booked several tests they are all done in the same visit.
Can I book several tests at once?
Yes. Use “Add to booking” on each test and then “Book” in the bar at the bottom — they go into one appointment and one payment. Home test kits are ordered separately, because they are posted to you.
How do I pay, and can I cancel?
Pay online when you book — by card or bank transfer — or at the clinic where that option is offered. You can cancel or reschedule up to 24 hours before your appointment for a full refund.
How do I get my results?
Results are released to your secure account and explained by our clinical team in a written summary, with a call where something needs talking through. Turnaround depends on the test: routine blood panels are quicker than genetic or DNA analysis, and we tell you what to expect at your appointment.
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