All Women's Blood Tests
Full Cardiac Risk Clinic test
Genetic risk · heart

Full Cardiac Risk

Our widest heart genetics panel — well over a hundred genes linked to inherited cardiomyopathies, arrhythmia syndromes, lipid disorders and aortic conditions.

Price £900 £884.99
Covers 134 genes
Type Clinic visit · ~15 min
Book just this test
Blood sample for DNA analysis — taken at 44 Crawford Street, Marylebone
No preparation needed. Bring details of any family heart history, including any sudden deaths.
Results explained by our clinical team
About this test

Everything you need to know about Full Cardiac Risk

Some of the most serious heart conditions are inherited and silent until they are not: hypertrophic and dilated cardiomyopathy, long QT and Brugada syndromes, familial hypercholesterolaemia and inherited weaknesses of the aorta. Finding them early changes what happens next — from medication and monitoring to advice about exercise and screening of relatives.

This panel analyses an extensive set of genes associated with those conditions, including MYBPC3, MYH7, TTN-related and other cardiomyopathy genes, the arrhythmia genes KCNQ1, KCNH2, SCN5A-family and RYR2, the lipid genes LDLR, APOB and PCSK9, and FBN1 and related aortopathy genes. A genetic test looks at the DNA you were born with. It tells you about inherited likelihood, not certainty: a variant can raise your risk without meaning you will develop the condition, and a clear result does not remove the everyday risk everyone carries. Results are explained to you by our clinical team, and we will say when a conversation with your GP or a genetics service is the right next step. Because the implications can be significant, every result is discussed with you by a clinician.

What's measured

What's included

134 genes in this test

ABCC9 ABCG5 ABCG8 ACTA1 ACTA2 ACTC1 ACTN2 AKAP9 ALMS1 ANK2 ANKRD1 APOA4 APOA5 APOB APOC2 APOE BAG3 BRAF CACNA1C CACNA2D1 CACNB2 CALM1 CALR3 CASQ2
Who it's for

Worth considering if

  • A close relative with cardiomyopathy, an inherited arrhythmia or an unexplained sudden death
  • Fainting during exercise, palpitations or an abnormal ECG without a clear cause
  • Very high cholesterol from a young age in you or your family
  • Planning a pregnancy with a family history of heart disease — some inherited conditions matter more in pregnancy
Important: A genetic test describes inherited likelihood, not certainty, and is not suitable for everyone. Our clinical team talks it through with you before the sample is taken and explains the result afterwards, including when a conversation with your GP or a genetics service is the right next step.
What to expect

Your visit

1

Book online

Add this test — and any others — to your booking, pick a time at the clinic and pay online. No preparation needed. Bring details of any family heart history, including any sudden deaths.

2

Your visit

About 15 minutes at 44 Crawford Street, Marylebone. Our clinical team takes your sample (blood sample for dna analysis) and answers any questions.

3

Results explained

The laboratory analyses your sample and your results are released to your secure account with a written explanation from our clinical team — and a call where something needs talking through.

Frequently Asked

Full Cardiac Risk — FAQs

Does this replace an ECG or heart scan?
No. Genetics tells you about inherited risk; an ECG, echocardiogram or stress test shows how your heart is actually functioning. The two are complementary, and if you have symptoms now you should see your GP or a cardiologist regardless of this test.
Why so many genes?
Inherited heart conditions are genetically varied — dozens of genes can cause cardiomyopathy alone. A broad panel gives a better chance of finding a relevant change in a family where the exact condition is not known.
What is a “variant of uncertain significance”?
A change in a gene whose effect is not yet established. These are common in large panels and are not treated as positive results. Our clinician explains any such finding and what, if anything, should be done about it.
What happens if a significant variant is found?
We explain it in detail and recommend referral through your GP to a cardiologist or inherited cardiac conditions service, who can arrange appropriate tests and advise relatives.
How long do results take?
A panel of this size takes longer than other tests. We give you the expected turnaround at your appointment and book a results conversation once the report is back.
Where is the test done?
44 Crawford Street, London W1H 1JS — a short walk from Marylebone and Edgware Road stations. Your sample is taken at the clinic by our clinical team; you do not need to bring anything.
How long does the appointment take?
About 15 minutes. If you have booked several tests they are all done in the same visit.
Can I book several tests at once?
Yes. Use “Add to booking” on each test and then “Book” in the bar at the bottom — they go into one appointment and one payment. Home test kits are ordered separately, because they are posted to you.
How do I pay, and can I cancel?
Pay online when you book — by card or bank transfer — or at the clinic where that option is offered. You can cancel or reschedule up to 24 hours before your appointment for a full refund.
How do I get my results?
Results are released to your secure account and explained by our clinical team in a written summary, with a call where something needs talking through. Turnaround depends on the test: routine blood panels are quicker than genetic or DNA analysis, and we tell you what to expect at your appointment.
More women's tests

Often booked together

Add several tests to one booking — they are all taken in the same visit.

Genetic risk Lifestyle and Nutrition DNA Test £240 £214.99
Genetic risk Breast & Ovarian Cancer Risk £620 £588.99
Genetic risk Bowel Cancer Risk Test £620 £588.99
Genetic risk Inherited Iron Overload Risk Test £95 £82.99
Genetic risk Lactose Intolerance Risk £120 £106.99
Genetic risk Inherited High Cholesterol Risk Test £615 £588.99
All Women's Blood Tests