Clinic test
Extended Cancer Risk
Our broadest hereditary cancer panel — more than 80 genes associated with inherited risk of breast, ovarian, womb, bowel, pancreatic, kidney, skin, endocrine and other cancers, including the BRCA and Lynch syndrome genes.
Everything you need to know about Extended Cancer Risk
Where a family history includes several different cancers, or a cancer that does not fit a single pattern, a single-cancer gene test can miss the explanation. The Extended Cancer Risk panel looks across more than 80 genes linked to hereditary cancer syndromes at once — the BRCA genes, PALB2, CHEK2 and ATM for breast and ovarian cancer; the Lynch syndrome genes (MLH1, MSH2, MSH6, PMS2, EPCAM) for bowel, womb and ovarian cancer; APC and MUTYH; TP53 and PTEN; and genes associated with endocrine, kidney and skin cancer syndromes.
A genetic test looks at the DNA you were born with. It tells you about inherited likelihood, not certainty: a variant can raise your risk without meaning you will develop the condition, and a clear result does not remove the everyday risk everyone carries. Results are explained to you by our clinical team, and we will say when a conversation with your GP or a genetics service is the right next step. Because the findings can affect relatives as well as you, every result from this panel is discussed with you in detail, and we support you in deciding what to share and how.
What's included
82 genes in this test
Worth considering if
- Several relatives with different cancers, or cancers at a young age
- A known inherited cancer syndrome in the family where the exact gene is not known
- A single-gene test that came back clear but a strong family history remains
- Women wanting a comprehensive inherited-risk review in one test
Your visit
Book online
Add this test — and any others — to your booking, pick a time at the clinic and pay online. No preparation needed. Bring as much family cancer history as you can gather.
Your visit
About 15 minutes at 44 Crawford Street, Marylebone. Our clinical team takes your sample (blood sample for dna analysis) and answers any questions.
Results explained
The laboratory analyses your sample and your results are released to your secure account with a written explanation from our clinical team — and a call where something needs talking through.
Extended Cancer Risk — FAQs
How does this differ from the Breast & Ovarian Cancer Risk test?
Will it tell me if I have cancer now?
What is the chance of finding a variant?
What happens if a variant is found?
How long do results take?
Where is the test done?
How long does the appointment take?
Can I book several tests at once?
How do I pay, and can I cancel?
How do I get my results?
Often booked together
Add several tests to one booking — they are all taken in the same visit.





